Pretreatment With Mifepristone Prior to Mirena Insertion

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Hypothesis: Pretreatment with mifeprsitone prior to Mirena placement will induce amenorrhea and reduce bleeding irrregularities during the initial months of Mirena use.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Karolinska Institutet
• Treatments: Levonorgestrel; Mifepristone

Criteria

Inclusion criteria:

• Pre-menopausal women, >/= 18 years of age.

• Desire of Mirena for contraception

• Good general health (as judged by; general physical examination

• Willing and able to participate after giving informed consent

Exclusion criteria:

• Any hormonal treatment or IUD use within 2 months prior to study start

• History of malignant disorder of the breast

• Any contraindication to mifepristone

• Pregnancy or breast feeding within 2 months prior to study start