Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation

• Status: Completed
• Trial end date: 2018-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Endotracheal intubation is common in the care of critically ill patients. Complications of airway management in this setting are frequently encountered and may be associated with an increased risk of death. The prevention of complications during urgent and emergent endotracheal intubation is a key focus for airway management research. Post-intubation hypotension (PIH), a common complication of endotracheal intubation in the critically ill, may be prevented by a bolus of intravenous fluid prior to the start of the procedure, but this approach has not been examined in a prospective trial. There are no randomized trials of intravenous fluid administration to prevent PIH in critically ill adults. The investigators propose a randomized trial of fluid loading to prevent PIH in critically ill adults.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Louisiana State University Health Sciences Center in New Orleans

Criteria

Inclusion Criteria:

• Patient is admitted to participating study unit

• Planned procedure is endotracheal intubation and planned operator is a provider expected to routinely perform endotracheal intubation in the participating unit

• Administration of sedation with or without neuromuscular blockade is planned

• Age ≥ 18 years old

Exclusion Criteria:

• Operator believes fluid loading to be absolutely indicated or contraindicated for the safe care of the patient

• Urgency of intubation precludes safe performance of study procedures

• Pregnancy

• Prisoners

• Age < 18 years old