The second visit of the Expanded Programme of Immunization when the child is 2 months old
(EPI-2) represents a unique opportunity to link the EPI and PMTCT programmes and to introduce
preventive and therapeutic rescue interventions in order to 1) Assess the efficacy of the
PMTCT cascade up to 2 months postpartum; 2) Allow at least 80% of HIV-1-infected infants
identified at the second EPI visit who were not involved in HIV care to initiate ARVs at the
earliest, but no later than 2 months after confirmation of HIV diagnosis; 3) Reduce HIV-1
transmission to less than 3% between 2 and 12 months among exposed children who completed the
second EPI visit
Phase:
Phase 2
Details
Lead Sponsor:
ANRS, Emerging Infectious Diseases French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)