Preventing Depression Recurrence in Diabetes

• Status: Completed
• Trial end date: 2004-10-01
• Target enrollment: 0
• Participant gender: All

Summary

To study the effectiveness of sertraline (Zoloft) in treating depression in adults with diabetes. The study will also determine whether depressed diabetic patients who have successfully responded to sertraline (Zoloft) are more likely to have depression recur if the sertraline (Zoloft) is discontinued.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Treatments: Sertraline

Criteria

Inclusion Criteria:

• 18-80

• Type 1 or Type 2 Diabetes

• Screen positive for depression

Exclusion Criteria:

• Are pregnant or lactating

• Are known to be hypersensitive to the drug

• Have a recent history of myocardial infarction or unstable heart disease

• Have severe hepatic disease or renal impairment (serum creatinine > 3 mg/dl)

• The subset of patients with psychiatric disorders thought to affect management (e.g., schizophrenia, alcohol and drug dependence) will also be excluded from participation