Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate the effectiveness of a preventative low-dose of Haloperidol to prevent delirium in patients undergoing a esophagectomy, pneumonectomy or thoracotomy.

Delirium is state of severe confusion and some symptoms include:

• Cannot think clearly

• Have trouble paying attention

• Have a hard time understanding what is going on around them

• May see or hear things that are not there. These things seem very real to them.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Indiana University
• Treatments: Haloperidol; Haloperidol decanoate

Criteria

Inclusion Criteria:

1. At least ≥ 18 years of age and older

2. Undergoing a possible or scheduled thoracotomy

3. English speaking

Exclusion Criteria:

1. History of Schizophrenia and Parkinson's disease

2. History of Severe Dementia

3. History of Alcohol Abuse

4. On Cholinesterase Inhibitors or Levodopa

5. Pregnant or Nursing

6. Corrected QT interval > 550 milliseconds at the time of randomization

7. History of Neuroleptic Malignant Syndrome or Haloperidol Allergy