Preventing Post-Stroke Depression

• Status: Completed
• Trial end date: 2008-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the effectiveness of both drug and non-drug treatments in preventing depression after a stroke.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Robert G. Robinson; University of Iowa
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Citalopram; Dexetimide

Criteria

Inclusion Criteria:

• Stroke within the last 120 days

Exclusion Criteria:

• DSM (Diagnostic and Statistical Manual) IV criteria for major or minor depressive disorder

• Heart, respiratory, kidney, or liver failure; severely disabling musculoskeletal disorder; or cancer

• Diagnosis of neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, Multiple System Atrophy, or Huntington's disease

• Pre-existing dementia or aphasia with severe language comprehension deficits

• Alcohol or substance abuse or dependence within the last 12 months

• Recurrent unipolar or bipolar disorder prior to the stroke