Preventing Urinary Tract Infections With E. Coli Nissle:
Status:
Recruiting
Trial end date:
2024-12-31
Target enrollment:
Participant gender:
Summary
Urinary tract infections (UTIs) account for 5-14% of pediatric emergency department visits
annually. At the moment, up to one third of children suffering of acute (UTI) will have a new
infection and there is a lack of effective methods for preventing secondary UTIs in young
children. Majority of UTIs in children are caused by intestinal bacteria of the patient,
mainly E. coli that colonizes gut of the patient. E. coli Nissle is a probiotic strain that
has been used successfully for treating acute gastrointestinal infections in children. The
strain has also been proved to be safe for infants and young children. E. coli Nissle could
be a potential solution for preventing recurrent urinary tract infections in children as it
competes with pathogenic bacteria that usually cause UTIs in children.
The aim of this study is to evaluate efficacy of E. coli Nissle strain in secondary
prevention of urinary tract infections in young children.
Phase:
Phase 4
Details
Lead Sponsor:
University of Oulu
Collaborators:
Helsinki University Central Hospital Kuopio University Hospital Tampere University Hospital Turku University Hospital