Prevention Relapse of Graves' Disease by Intrathyroid Injection of Dexamethasone

• Status: Completed
• Trial end date: 2009-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Antithyroid drugs are widely used in treatment of Graves' disease (GD), but after therapy withdrawal, relapse rate is very high. The aim this trail is to evaluate the effects of intrathyroid injection of dexamethasone combined with antithyroid drugs on patients with newly diagnosed GD.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Xiao-Ming Mao
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Methimazole

Criteria

Inclusion Criteria:

• Newly diagnosed of Graves' Disease

Exclusion Criteria:

• Pregnancy

• Allergy to ATD, Alanine aminotransferase (ALT) or asparate aminotransferase (AST) above 2 times of upper normal range

• Non-compliance because of psychiatric or other serious diseases, or unwillingness to participate in the study.