Prevention of Akute Kidney Injury, Hearttransplant, ANP
Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
Prospective, blinded, placebo-controlled trial. Patients: Adult patients (>18 years of age)
undergoing de novo Htx, with a preoperative GFR > 30ml/min, not receiving an ABO-incompatible
organ with an ischemia time of > 6 hours. A donor age > 70 years is an exclusion criteria.
Intervention: Infusion of h-ANP fore five days, starting at the induction of anesthesia.
Outcome: Kidney function, evaluated with serum creatinine day 1-7 and kidney clearance, 4-5
Days after Htx plus after 3 and 12 months.