Prevention of Delayed Nausea A Phase III Double-Blind Placebo-Controlled Clinical Trial
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Antiemetic drugs, such as granisetron, dexamethasone, prochlorperazine,
aprepitant, and palonosetron, may help lessen or prevent nausea. It is not yet known which
combination of antiemetic drugs is more effective in preventing nausea caused by
chemotherapy.
PURPOSE: This randomized phase III trial is comparing different combinations of granisetron,
dexamethasone, prochlorperazine, aprepitant, and palonosetron to see how well they work in
preventing nausea in patients undergoing chemotherapy for breast cancer.