Prevention of Ectopic Bone Related Pain and Disability After Hip Replacement Surgery With Peri-Operative Ibuprofen
Status:
Completed
Trial end date:
2004-05-01
Target enrollment:
Participant gender:
Summary
The primary aim of this randomised trial is to determine the effects of a short
peri-operative course of treatment with a non-steroidal anti-inflammatory drug (NSAID),
ibuprofen, on the long-term consequences of ectopic bone formation in patients undergoing
elective total hip replacement surgery. The specific hypotheses to be tested at that 6 to 12
months after surgery, patients assigned post-operative ibuprofen will have less self-reported
pain and physical disability, greater health-related quality of life and reduced ectopic bone
formation compared with those assigned placebo.
Phase:
Phase 4
Details
Lead Sponsor:
The George Institute
Collaborators:
Medical Benefits Fund Australia Pty Ltd National Health and Medical Research Council, Australia