Prevention of Gastrostomy-Related Wound Infection by Vancomycin in Carriers of Methicillin-Resistant Staphylococcus Aureus.

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to determine whether vancomycin with cefazoline is superior to vancomycin with placebo in preventing gastrostomy-related wound infection in carriers of methicillin-resistant staphylococcus aureus (MRSA).

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Geneva
• Treatments: Vancomycin

Criteria

Inclusion Criteria:

• PEG insertion in a patient with a swab positive for MRSA during the 4 weeks preceding PEG insertion

Exclusion Criteria:

• Age < 18 years

• No informed consent obtained either from the patient or from his legal representative

• Contraindication to the administration of cefazolin or of vancomycin

• Systemic administration of antibiotics effective against MRSA during the week prior to the procedure

• Technique of PEG insertion different from the standard pull technique proposed by the physician in charge and the gastroenterologist

• Patients requiring antibiotic prophylaxis of endocarditis