Prevention of Malaria During Pregnancy Using Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine: Malawi
Status:
Completed
Trial end date:
2005-03-01
Target enrollment:
Participant gender:
Summary
In Malawi, the standard of care to prevent malaria during pregnancy at the time of the study
was a two dose sulfadoxine-pyrimethamine intermittent protective treatment (SP IPT) regimen
administered in the second and third trimester of pregnancy. In this investigation, this two
dose strategy was compared to a monthly SP regimen. The objective for the study was to
determine the efficacy of the different regimens for HIV positive and HIV negative women in
the prevention of placental malaria.
Phase:
N/A
Details
Lead Sponsor:
Centers for Disease Control and Prevention
Collaborator:
Ministry of Health and Population, Malawi
Treatments:
Fanasil, pyrimethamine drug combination Pyrimethamine Sulfadoxine