Prevention of Narcotic-Induced Nausea

• Status: Terminated
• Trial end date: 2009-11-01
• Target enrollment: 0
• Participant gender: All

Summary

We are doing this study to find out if extra medicine is needed to avoid the chance of nausea sometimes linked to narcotic pain medicine (for example, morphine, dilaudid, fentanyl). Some doctors always give medicine to prevent the possible side effect of nausea, while others do not. We are looking to see if this extra medicine is helpful in preventing nausea. The goal is to screen all patients with pain and enroll enough subjects to reach our goal of 164 evaluable study participants.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Christiana Care Health Services
• Treatments: Narcotics; Promethazine

Criteria

Inclusion Criteria:

1. Patient in Christian Care Emergency Department

2. Require intravenous narcotics for painful condition

3. ≥18 years of age

4. Able to visually rate amount of pain and nausea

Exclusion Criteria:

1. Hypersensitivity to promethazine or opioids

2. Patient requesting anti-emetic at enrollment

3. Narcotic administration in last 6 hours

4. Pregnancy or currently breast-feeding

5. Known seizure disorder

6. Medical Instability