Overview

Prevention of Neonatal Respiratory Distress Syndrome With Antenatal Steroid Administration

Status:
Completed

Trial end date:
1983-08-01

Target enrollment:
0

Participant gender:
All

Summary

To determine the effect of corticosteroids, administered 24 to 48 hours before parturition, on the incidence of neonatal respiratory distress syndrome (RDS) and to determine whether the therapy has any adverse short- or long-term (up to 36 months) effects on the infant. Secondarily, to determine whether the therapy has any adverse short-term effects on the mother and to determine whether morbidity rates for neonatal respiratory distress syndrome as well as total and cause-specific infant mortality rates differ between mothers who received antenatal steroids and those who received conventional medical care.

Phase:

Phase 3

Accepts Healthy Volunteers?

Details

Lead Sponsor:

National Heart, Lung, and Blood Institute (NHLBI)

Treatments:

Dexamethasone

Criteria

Male and female fetuses and infants; pregnant women with anticipated premature delivery and
gestational age between 26 and 37 weeks.