Prevention of Post Operative Bone Loss in Children
Status:
Completed
Trial end date:
2011-08-01
Target enrollment:
Participant gender:
Summary
Hypothesis: one-dose pamidronate will prevent post-operative bone loss in children at risk
for low bone density
Plan: children with chronic disease such as CP, spina bifida, etc. will be recruited pre
operatively and studied with DXA scan. After surgery, children will be randomized to receive
either pamidronate or saline. Repeat DXA scan will determine bone lost after end of
immobilization or nonweightbearing.