Prevention of Post-Operative Nausea and Vomiting With Propofol Infusion

• Status: Not yet recruiting
• Trial end date: 2026-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to clarify whether or not a low-dose propofol infusion can effectively prevent postoperative nausea and vomiting (PONV) in patients who have a documented history of PONV and/or motion sickness.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Milton S. Hershey Medical Center
• Treatments: Propofol

Criteria

Inclusion Criteria:

1. Undergoing general anesthesia for elective surgery

2. Documented history of Patient's self-disclosure of PONV and/or motion sickness during pre-anesthesia discussions

3. No documented allergy/adverse reaction to propofol

4. English speaking

5. At least 18 years of age

Exclusion Criteria:

1. Any anti-nausea medication taken within 24 hours prior to surgery

2. Unable to provide consent independently

3. Allergy or adverse reaction to propofol

4. Emergency surgery