Prevention of Shivering After Spinal Anesthesia

• Status: Completed
• Trial end date: 2021-08-19
• Target enrollment: 0
• Participant gender: All

Summary

Recently, ketamine and dexmedetomidine have been used to prevent shivering during anaesthesia, with good results. Ketamine (a competitive NMDA receptor antagonist) plays a role in thermoregulation at various levels and ketamine, has been shown to inhibit postoperative shivering in some reports and studies.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Pakistan Air Force (PAF) Hospital Islamabad
• Treatments: Dexmedetomidine; Ketamine

Criteria

Inclusion Criteria:

• Patients aged 20-50 years.

• Both genders

• ASA physical status I and II

• Undergoing lower abdominal or lower limb surgeries under spinal anaesthesia

Exclusion Criteria:

• Patients with history of thyroid and neuromuscular diseases

• Patients with severe hypovolemia

• Patients with febrile illness

• Patients who required blood transfusion during surgery

• Patients with body temperature ≤ 36˚C or ≥ 38˚C on thermometer