Preventive Application of GnRH Antagonist on Early OHSS
Status:
Unknown status
Trial end date:
2018-03-01
Target enrollment:
Participant gender:
Summary
Ovarian hyperstimulation syndrome is an iatrogenic complication of controlled ovarian
stimulation. Ovarian hyperstimulation syndrome prevention is a multistage process and more
important than treatment.Preventive administration of GnRH antagonist for high risk OHSS
patients from the day of oocyte retrieval is not investigated. Besides, the relevant
mechanism is not clear yet. Here we designed a prospective randomized study to investigate
whether GnRH anatagonist treatment after oocyte retrieval is more effective in preventing
early ovarian hyperstimulation syndrome development than traditional aspirin preventive
administration in women at high risk for OHSS.