Preventive Sodium Lactate and Traumatic Brain Injury

• Status: Completed
• Trial end date: 2011-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this study is to evaluate the effect of preventive intravenous infusion of half molar sodium lactate on the onset of hypertensive intracranial episodes in severe head trauma. The investigators hypothesize that preventive intravenous administration of sodium lactate will decrease the number of treatments required to decrease intracranial pressure during 48 hours.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Institut d'Anesthesiologie des Alpes Maritimes
• Collaborators: Medical University of Grenoble; Université de Nice Sophia Antipolis

Criteria

Inclusion Criteria:

• severe head trauma with a glasgow coma scale less than 9

Exclusion Criteria:

• prehospital cardiac arrest

• severe hemorrhage shock

• severe circulatory or respiratory failure

• medullar trauma

• prehospital osmotherapy