Primary Prophylaxis of Gastric Variceal Bleed

• Status: Unknown status
• Trial end date: 2020-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to study the efficacy of endoscopic cyanoacrylate injection versus balloon-occluded retrograde transvenous obliteration in the prevention of gastric variceal bleeding.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: West China Hospital
• Treatments: Polidocanol

Criteria

Inclusion Criteria:

1. Cirrhosis

2. Patients with high risk gastric varices (GOV2 or IGV1)

3. Presence of gastrorenal shunt

Exclusion Criteria:

1. Acute bleed or past history of bleed from gastric varices

2. Previous treatment of gastric varices.

3. Non-cirrhotic portal hypertension

4. Contraindications to cyanoacrylate injection or BRTO

5. Portal cavernoma

6. Hepatorenal syndrome

7. Proven malignancy including hepatocellular carcinoma

8. End-stage renal disease under renal replacement therapy;

9. Cardiorespiratory failure

10. Pregnancy or patients not giving informed consent for endoscopic procedures