Probiotics for Eradication of Carbapenem Resistant Klebsiella Pneumonia
Status:
Unknown status
Trial end date:
2010-09-01
Target enrollment:
Participant gender:
Summary
Infection by Klebsiella pneumonia producing class A carbapenemases is a major clinical and
public health problem in Israel and worldwide. The aim of this study is to determine the
safety and efficacy of alteration of the gut microflora by probiotics, alone or in
combination with mechanical bowel cleansing, as a strategy to eradicate colonization of the
gastrointestinal tract by CRKP. We hypothesize that administration of probiotics will
decrease the rate of GI colonization by CRKP.