Probiotics in Patients With Primary Sclerosing Cholangitis
Status:
Unknown status
Trial end date:
2006-05-01
Target enrollment:
Participant gender:
Summary
PSC is a progressive liver disease without effective medical treatment. There is often
co-existent ulcerative colitis. Probiotics (bacterial food supplements) have been shown to
benefit patients with ulcerative colitis. In the current protocol potential beneficial
effects of probiotics on liver biochemistry and liver related symptoms as pruritus are being
assessed in 12 PSC patients in a randomized controlled cross over study (3 months probiotics,
1 one wash-out and 3 months placebo).