Progesterone for Prevention of Preterm Birth in Women With Short Cervix: Randomized Controlled Trial

• Status: Completed
• Trial end date: 2006-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of our study is to evaluate the effect of use of prophylactic vaginal progesterone on the incidence of severe preterm delivery, defined as delivery before 33+6 weeks in women with a short cervical length of 15mm.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: King's College Hospital NHS Trust
• Treatments: Progesterone

Criteria

Inclusion Criteria:

• All women with singleton or twin pregnancies attending for routine ultrasound examination at 20-25 weeks of gestation with a short cervical length (<15 mm).

Exclusion Criteria:

• Women with major fetal abnormalities,

• Painful regular uterine contractions, or history of ruptured membranes or cervical cerclage in-situ were excluded from screening.