Prognostic Predictors of Response to Hypoglycemic Therapy
Status:
Recruiting
Trial end date:
2020-05-01
Target enrollment:
Participant gender:
Summary
This is a randomized controlled trial aimed to determine highly specific personified
predictors of response to the therapy by different groups of hypoglycemic drugs (SGLT-2
inhibitors, DPP-4 inhibitors, GLP-1 receptor agonists, sulfonylureas) in patients with type 2
diabetes mellitus, develop an algorithm of personalized therapy based on them, design an
organizational and methodological model for prevention of the cardiovascular complications,
and create an automated decision-making system for therapy selection to reduce the incidence
of cardiovascular events and related adverse outcomes compared to the traditional approach.
This is an interventional, randomized controlled trial, open-label study.
Phase:
Phase 4
Details
Lead Sponsor:
Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health