Prolonged Treatment for Infected Abortion After Hospital Discharge.

• Status: Terminated
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Patients with infected abortion will be treated with dilatation and curettage, intravenous antibiotics. The purpose of this study is to verify if it is necessary to keep the use of oral antibiotics after hospital discharge.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital de Clinicas de Porto Alegre
• Treatments: Doxycycline; Metronidazole

Criteria

Inclusion Criteria:

• History of intrauterine manipulation with contaminated objects.

• Vaginal secretion with fetid odor

• Presence of pus flowing through the cervical uterine

• Presence of peritonitis

• Leucocytosis (> 14,000 leucocytes/mL)

• Vasodilatation, bounding pulse and paradoxically warm periphery with tachycardia (Heart rate> 110 bpm)

• Cyanosis and/or paleness

• tachypnea(> 30mpm)

• Arterial hypotension (SAP< 90mmHg)

• Oliguria

• Fever (> or = than 37,8°C)

Exclusion Criteria:

• Refusal to participate in the project

• Prior use of antibiotics within one week

• Known allergy to Doxycycline or Metronidazole

• Presence of tubo-ovarian abscess