Proper Dosage of Ketamine in Intravenous Regional Anesthesia

• Status: Unknown status
• Trial end date: 2005-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Ketamine added to Lidocaine can increase duration of pain relief following intraveonous regional anesthesia (IVRA). The purpose of this dose response study is to determine the minimum effective dosage of intravenous Ketamine, added to 3 mg/kg of Lidocaine. We anticipate that one dosage will provide us with the proper balance between sufficient anesthesia and minimal side effects.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Health Network, Toronto
• Treatments: Ketamine

Criteria

Inclusion Criteria:

1. Age: 18-70

2. Weight: 50-100 kg

3. ASA: I, II, III

4. Carpal tunnel syndrome surgery, tenolysis, ganglion removal or any peripheral hand surgery that can be done by IVRA.

Exclusion Criteria:

1. Contraindication to IVRA such as sickle cell disease.

2. Any known hypersensitivity reaction to Ketamine.

3. History of chronic pain or regular medication with analgesics.

4. History of opioid dependence.

5. Drug of alcohol abuse.

6. Psychiatric disorder.

7. Allergy to acetaminophen or codeine