Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY)
Status:
Completed
Trial end date:
2021-03-01
Target enrollment:
Participant gender:
Summary
The Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) trial is the first ever
international multi-center randomized controlled trial in bone cancer surgery. In order to
avoid amputation for bone cancer in the leg, complex limb-saving operations are performed.
However, infections with devastating complications following surgery are common. Surgeons
from across the world will randomize patients to receive either short- or long-duration
antibiotic regimens after surgery with the goal of identifying the best regimen to reduce
these infections.
Phase:
Phase 3
Details
Lead Sponsor:
McMaster University
Collaborators:
Canadian Cancer Society (CCS) Canadian Cancer Society Research Institute (CCSRI) Canadian Institutes of Health Research (CIHR) Orthopedic Research and Education Foundation The Physicians' Services Incorporated Foundation