Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial
Status:
Completed
Trial end date:
2018-09-01
Target enrollment:
Participant gender:
Summary
Surgeons commonly prescribe post operative prophylactic antibiotics after sinus surgery.
There is minimal data to support this. The investigators' study will aim to demonstrate that
patients' quality of life and rate of post operative infection is the same whether they
receive or do not receive antibiotics post operatively. The investigators hypothesis is that
the disease specific quality of life of patients taking post-operative antibiotics is not
inferior to the quality of life of patients who do not take post-operative antibiotics, and
the rate of post-operative infections are the same. The investigators' specific aim is to
compare validated symptom scores between post-operative populations who are given or are not
given antibiotics. Rates of infections in the first 10 days after surgery will be recorded.
The investigators will also compare endoscopic grades of sinus cavities during the
post-operative follow up exams as an additional outcome measure.