Prophylactic Ethanol Lock Therapy (ELT) in Patients on Home Parenteral Nutrition

• Status: Terminated
• Trial end date: 2016-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is being implemented to identify the role of prophylactic use of ethanol lock in adult patients on home parenteral nutrition (HPN). Central catheter related blood stream infection is a major complication in patients on HPN. The investigators hypothesize that the prophylactic use of ELT will decrease the number of catheter related blood stream infections compared to the control group. The investigators further hypothesize that with the introduction of prophylactic ELT, the number of infections will decrease.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mayo Clinic
• Treatments: Calcium heparin; Ethanol; Heparin

Criteria

Inclusion Criteria:

• Newly started on Home parenteral Nutrition and anticipated duration >3 months.

• Not previously on Home Parenteral Nutrition.

• Providing consent.

• Patients with non-medicare insurance.

• Patients with medicare insurance and a supplementary insurance.

• Patients with single lumen Hickman® catheters.

• No known alcohol addiction.

Exclusion Criteria:

• Failure to provide consent

• Patients with medicare insurance and no other supplemental private insurance

• Patients with a catheter type other than a single lumen Hickman®

• Patients who are on HPN for less than three months

• Pregnant patients

• Patients who have previous proven addiction and dependence to alcohol.

• Patients lacking capacity to provide consent

• Patients who are not be managed by HPN team at investigator's institution