Prophylactic Nepafenac and Ketorolac Versus Placebo in Patients Undergoing Cataract Surgery

• Status: Completed
• Trial end date: 2011-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Assess prophylactic efficacy of topical non-steroidal anti-inflammatory drops in preventing macular edema. Patient undergoing uncomplicated cataract surgery will be enrolled and randomized to nepafenac, ketorolac, or placebo. Follow-up will occur at 1 month with ocular coherence tomography (OCT).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Queen's University
• Treatments: Ketorolac; Ketorolac Tromethamine; Nepafenac

Criteria

Inclusion Criteria:

• Ability to give informed consent

• Age 18 years and older

Exclusion Criteria:

• Any pre-existing retinal disease (e.g., diabetic retinopathy, vein occlusion, exudative macular degeneration, etc.)

• Previous uveitis

• Previous intraocular surgery

• Allergy or hypersensitivity to NSAIDs

• Complicated cataract surgery