Prophylactic Tamsulosin Use for Prevention of Post-Operative Urinary Retention

• Status: Terminated
• Trial end date: 2017-12-01
• Target enrollment: 0
• Participant gender: Male

Summary

This randomized open-label study will be comprised of 2 cohorts: one control group and one treatment group. The trial will be conducted as an open label randomized trial to evaluate the efficacy of tamsulosin in the prevention of post-operative urinary retention. The study will include pre- and post-surgical evaluations of patients including symptoms of urinary retention and any adverse effects contributable to the study medication.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Rochester
• Treatments: Tamsulosin

Criteria

Inclusion Criteria:

• Any male age 40 or older

• Scheduled to undergo one of the planned surgeries (thoracic, general, or urologic)

• Ability to give informed consent

Exclusion Criteria:

• Current use of alpha blocker

• Current use of a strong CYP 3A4 inhibitors

• Any allergy to tamsulosin, alpha-blocker medication class, or anaphylaxis allergy to sulfate containing medications

• Patients with any upcoming surgery for cataracts

• Currently enrolled in a clinical trial

• Inability to give informed consent