Prophylactic Use of Intraumbilical Vein Oxytocin Injection in The Management of Third Stage of Labor
Status:
Unknown status
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
The third stage is the interval between delivery of the infant and delivery of the placenta.
This stage averages 10 minutes and is considered prolonged if it lasts longer than 30
minutes, placental separation occurs as a result of continued uterine contractions, continued
contractions control blood loss by compression of spiral arteries and also result in
migration of the placenta into the lower uterine segment and then through the cervix.
The intra-umbilical vein injection of 10 IU of oxytocin is recommended as a first line of
treatment for retained placenta. Despite this recommendation, the method has yet to make its
way into routine practice, probably because of the lack of a large substantive randomized
controlled trial, and lingering doubts over which uterotonic to use and at what dosage.
The purpose of this study is to evaluate the effect of intraumbilical vein injection of
oxytocin on reducing the duration of the third stage of labor and the need for manual
delivery of placenta, ,in addition to reduce blood loss during third and fourth stage of
labor and decrease incidence of rtained placenta in comparison with inraumblical injection of
normal saline.
This is a prospective randomized control trial conducted at Ain Shams University Maternity
Hospital. This study included 240 term pregnant women in labor admitted to the labor ward,
They were divided into Two groups :
Group (A):
The experimental group, 10 units of oxytocin will be injected into the umbilical vein at the
most proximal site to the placenta after clamping and cutting of the umbilical cord.
Group (B):
The control group, 1 mL normal saline will be injected into the umbilical vein at the most
proximal site to the placenta after clamping and cutting of the umbilical cord.