Prophylatic Effect Preoperative Antibiotics With Mechanical Bowel Preparation in SSIs
Status:
Recruiting
Trial end date:
2021-10-31
Target enrollment:
Participant gender:
Summary
Surgical site infection (SSI) is a major postoperative complication after abdominal surgery
especially in colorectal field, which significantly increases length of stay (LOS),
readmission incidence and expense. Therefore, identification of the effective method to
reduce SSI incidence is critically important. Combination of oral antibiotics and mechanical
bowel preparation was reported with lower SSIs and LOS in some retrospecitve data analysis,
however a prospective randmized controlled trial was absent. Herein, the current randomized
controlled trial comparing MBP+OA with MBP alone in postoperative complications in order to
guide clinical practise was conducted.