Propofol Sedation During Upper Endoscopy With and Without Topical Pharyngeal Anesthesia

• Status: Completed
• Trial end date: 2010-05-01
• Target enrollment: 0
• Participant gender: All

Summary

It is unclear whether a topical pharyngeal anesthesia adds any benefit to the upper gastrointestinal endoscopy under a propofol sedation. We hypothesize that a topical pharyngeal anesthesia does not ease the upper gastrointestinal endoscopy under propofol sedation. The aim of this study is therefore to quantify the impact of a topical pharyngeal anesthesia to the upper gastrointestinal endoscopy in patients sedated with propofol.

Patients will be randomized to receive a topical pharyngeal spray containing either an anesthetic drug (lidocaine 10%) or a placebo. Thereafter the upper endoscopy will be conducted in its standard manner.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Basel, Switzerland
• Treatments: Anesthetics; Lidocaine; Pharmaceutical Solutions; Propofol

Criteria

Inclusion Criteria:

• Scheduled diagnostic upper endoscopy

• Wish to be sedated

• ASA class I - III

• Signed informed consent

Exclusion Criteria:

• Emergency medical examinations

• Therapeutic Endoscopy

• ASA class IV

• Pregnancy

• Known allergy to propofol or lidocaine