Propofol and Dexmedetomidin vs Midazolam Intraoperative Sedation and POCD

• Status: Recruiting
• Trial end date: 2023-07-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will examine the effect of intraoperative sedation with midazolam, propofol and dexemdetomidine on the occurrence of postoperative cognitive impairment in patients undergoing surgical treatment of pertrochanteric fracture of the femur.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Osijek University Hospital
• Collaborator: Josip Juraj Strossmayer University of Osijek
• Treatments: Dexmedetomidine; Midazolam; Propofol

Criteria

Inclusion Criteria:

• Pertrochanteric fracture surgery

• Informed consent signed

Exclusion Criteria:

• MMSE before surgery < 17

• Allergy on midazolam, propofol or dexemdetomidine

• Contraindication for neuroaxial anesthesia