Propofol-butorphanol Anesthesia During Uterine Curettage
Status:
Completed
Trial end date:
2009-07-01
Target enrollment:
Participant gender:
Summary
Uterine curettage is usually performed under the anesthesia of propofol-fentanyl or
para-cervical block,of which generally has significant incidence of respiratory depression
which increases the demand on intraoperative monitoring, or has unavoidable insufficient
blockade which results in intraoperative suffering of pain. Butorphanol is an analgesic with
combined effects on mu and kappa opioid receptors leading to a role as analgesia and
sedation. The investigators hypothesized that combined propofol with butorphanol during
uterine curettage would produce optimal effectiveness of these two drugs by adding sedative
and analgesic effects together. In addition, it would decrease the intraoperative consumption
of propofol without increase the incidence of side effects. Furthermore, such combination
would alleviate postoperative pain.