Propranolol Treatment of Traumatic Memories (PTTM)

• Status: Unknown status
• Trial end date: 2011-09-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will compare the responses of subjects with traumatic memories of varying vintages to either propranolol or placebo in a double-blind setting. It is hypothesized that those subjects who receive propranolol will experience less emotional distress when the memory is subsequently reactivated and less spontaneous re-experiences.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mela, Mansfield, M.D.
• Treatments: Propranolol

Criteria

Inclusion Criteria:

• Male or female adults between 18 and 70 years of age

• A traumatic memory, as an isolated symptom or in the context of Post-traumatic Stress Disorder

Exclusion Criteria:

• Pregnancy

• Breastfeeding

• Current treatment with either a beta-blocker or a corticosteroid medicine

• Medical contraindications, as outlined in the Compendium of Pharmaceutical and Specialties and the Product Monograph

• Subjects who want to retain every aspect of their memory for the traumatic event, as some memory could be lost