Prospective Analysis of the Use of N-Acetylcysteine and Vitamins in the Treatment of TBI in Geriatric Patients

• Status: Completed
• Trial end date: 2021-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the administration of N-Acetyl-cysteine in combination with multi-vitamins/minerals in geriatric population (>60 years of age) who have experienced a traumatic brain injury.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: HonorHealth Research Institute
• Treatments: Acetylcysteine; N-monoacetylcystine; Vitamins

Criteria

Inclusion Criteria:

• 60 years or older

• present to emergency department within 3 hours of documented TBI

Exclusion Criteria:

• patients without TBI

• patients with a history of TBI greater than 3 hours prior to presentation

• patients under the age of 60

• currently enrolled in an ongoing research study

• patients who at baseline prior to the TBI, cannot participate in cognitive function testing (aphasia, severe dementia, non verbal; prior to TBI)

• Patients who are unable to tolerate PO medications within 3 hours of sustaining TBI.