Prospective, Cross Over Gabapentin vs Amitriptyline Study on Patients Suffering From Masticatory Muscle Pain

• Status: Unknown status
• Trial end date: 2017-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is comparing two drugs efficacy for the treatment of pain originates from masticatory muscles. The two drugs are - Amitriptlyne (amitriptyline) and Gabapentin (gabapentin), both of them are common use in for the treatment of chronic pain Methods - patient that is diagnosed as suffering from myofacial pain, will receive one of the medications above (Gabapentin or amitriptyline) for one month only, after which he will be invited to pain clinic for control. Two weeks after that, the patient will start taking the other drug for 1 month and then invited again to the department for recall and continue standard treatment . The patient can choose whether to continue medication with one of the drugs or stop this medication treatment. Total duration of the experiment is two and a half months.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Doron Aframian
• Treatments: Amitriptyline; Amitriptyline, perphenazine drug combination; Gabapentin; gamma-Aminobutyric Acid

Criteria

Inclusion Criteria:

• Patients who suffer from chronic pain more than 3 months prior to arrival

• patients who are capable to reach all the visits in the clinic

• Not pregnant women

Exclusion Criteria:

• Patients with other types of non-muscle origin pain

• Patients without a clear diagnosis.

• Patients who are not originally designated to medication treatment (regardless experiment) for various reasons eg pregnancy.

• Patients who are not interested in medication.

• Patients who are not interested or unable to cooperate.

• Patients who suffer from chronic pain less than 3 months prior to arrival

• Pregnant women