Prospective Evaluation of Perioperative Steroid Dosing on Postsurgical Edema in Orthognathic Surgery
Status:
Completed
Trial end date:
2019-12-31
Target enrollment:
Participant gender:
Summary
The current standard of care at the Oral and Maxillofacial Department at the CDHA is the use
of one gram of methylprednisolone administered intravenously prior to orthognathic surgery.
This is largely based on the work of Habal. The administration of one gram of
methylprednisolone can be concerning for the anesthesiologist since this is an unusually
large dose of steroid in comparison to use in other surgical specialties. As with most
medications, the chances of steroid-related complications increase with increasing doses of
steroids.
The researchers are proposing a prospective, double-blind randomized control trial to
determine if a smaller dose of methylprednisolone (125mg) can be used safely and effectively
instead of one gram of methylprednisolone.