Prospective Randomized Evaluation of Antibiotic Regimen Following Appendectomy for Perforated Appendicitis

• Status: Completed
• Trial end date: 2007-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare traditional triple antibiotic therapy against dual single day dosing antibiotic therapy in the management of perforated appendicitis in children.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Children's Mercy Hospital Kansas City
• Treatments: Ampicillin; Anti-Bacterial Agents; Ceftazidime; Clindamycin; Clindamycin palmitate; Clindamycin phosphate; Gentamicins

Criteria

Inclusion Criteria:

• All patients under 18 years of age found to have perforated appendicitis at the time of operation for appendicitis and whose parents give informed permission will be included in the study.

Exclusion Criteria:

• Patients with a normal or non-perforated appendix at the time of appendectomy, those without parental permission, or those with a documented allergy to any of the antibiotics used in either regimen will be excluded from the study. Patients 18 years or older will not be included in the study