Prospective Randomized Trial Between Needle Fasciotomy and Xiapex for Dupuytrens Contracture

• Status: Unknown status
• Trial end date: 2021-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate whether percutaneous needle fasciotomy is as effective for treating Dupuytrens contracture as Xiapex. Immidiate treatment effect is to be investigated, as iskontracture size after 5 years. Contracture size after one and three years, and subjective hand function is also to be investigated.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Oslo University Hospital

Criteria

Inclusion Criteria:

• symptomatic Dupuytrens contracture with palpable cord, involving MCP, total contracture size over 30 degrees

Exclusion Criteria:

• previous treated dupuytrens contracture same hand

• more than tree fingers involvement

• we will not include thumbs

• other things affecting hand function

• ASA>3

• expected to live under five years

• Tetracycline treatment within two weeks

• pregnancy

• nursing

• allergy to clostridium histolyticum

• participant in other trial