Prospective Study of First-line Antibiotic Therapy for Early-stage Gastric MALT Lymphoma for Treatment Outcome
Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
1. The complete histological and molecular remission rate for antibiotics as 1st-line
therapy for Hp-positive early-stage gastric lg- and hg-MALT lymphoma
2. The durability of complete histological remission after antibiotics
3. The usefulness of pattern of NF-kB and BCL-10 by IHC staining in prospectively
predicting the Hp-dependence of gastric lg- and hg-MALT lymphoma
4. The frequency of t(11;18) translocation in gastric lg- and hg-MALT lymphoma in Taiwan.
5. The association between the CYP2C18/19 genetic polymorphisms and eradication of Hp
infection after antibiotics.
Phase:
N/A
Details
Lead Sponsor:
National Health Research Institutes, Taiwan
Collaborators:
Chang Gung Memorial Hospital Changhua Christian Hospital Chi Mei Medical Hospital China Medical University Hospital National Taiwan University Hospital Tri-Service General Hospital