Prostacyclin's Effect on Platelet Responsiveness

• Status: Completed
• Trial end date: 2008-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The researchers investigated the influence of a prostacyclin analogue (PGIA) versus unfractionated heparin (UFH) on ex vivo platelet function, during continuous venovenous hemodiafiltration.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Catholic University of the Sacred Heart
• Treatments: Anticoagulants; Calcium heparin; Epoprostenol; Heparin; Tezosentan

Criteria

Inclusion Criteria:

• critically patients ill patients with acute kidney failure (AKI) needing renal replacement therapy

Exclusion Criteria:

• therapy with aspirin or other non-steroidal anti-inflammatory drugs in the previous 7 days

• concomitant treatment with other extracorporeal organ-assist devices any other drug affecting coagulation or platelets