Protective Effect of Tranexamic Acid on Shedding of the Endothelial Glycocalyx in Patients Undergoing Spinal Fusion Surgery
Status:
Completed
Trial end date:
2020-08-12
Target enrollment:
Participant gender:
Summary
The aim of this study was to determine whether the administration of tranexamic acid in
patients undergoing lumbar spinal fusion surgery can inhibit damage in endothelial glycocalyx
layer. As a prospective double blinded randomized placebo-controlled trial, the investigators
detect and compare the changes in concentrations of serum syndecan-1 and heparan sulfate
before and after surgery.