Proteomics for Identification of Hyperoxia-induced Changes in Protein Expression
Status:
Unknown status
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
Aim of the present study is to investigate the influence of hyperoxia on the protein
expression using the differential analysis of protein expression in tissues (proteomics). In
the study, blood and urine samples will be collected from participants who undergo a short
term hyperoxia using 100% oxgen for 3 hours.
Here, gel electrophoresis, protein separation and mass spectroscopy allow to identify
affected proteins. Based on these results, different induction factors of proteins will be
determined and then assessed using a bioinformatic network analysis regarding the cellular
influence.