Proton Pump Inhibitor Preventing Upper Gastrointestinal Injury In Patients On Dual Antiplatelet Therapy After CABG
Status:
Recruiting
Trial end date:
2022-09-30
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare the efficacy and safety for 12- vs. 1-month of
pantoprazole treatment in preventing dual antiplatelet therapy (DAPT)-related upper
gastrointestinal mucosal injury after coronary artery bypass grafting (CABG).
To date, there has been no study using esophagogastroduodenoscopy (EGD) to compare the
differences in upper gastrointestinal mucosal injury (including reflux esophagitis) after 6
and 12 months of PPI treatment combined with two different DAPT regimens (clopidogrel plus
aspirin or ticagrelor plus aspirin).