Proton Pump Inhibitor Treatment Stop

• Status: Completed
• Trial end date: 2007-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine how many chronic users of antisecretory medication can stop after a test for a bacteria associated with peptic ulcer disease.

This is evaluated in a discontinuation trial.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Odense University Hospital
• Collaborators: Apotekerfonden af 1991; AstraZeneca; Danish College of General Practitioners; Research Unit of General Practice, Odense; The Danish Medical Research Council; University of Southern Denmark
• Treatments: Esomeprazole; Proton Pump Inhibitors

Criteria

Inclusion Criteria:

• Use of antisecretory medication for more than 2 months during the last 6 months

Exclusion Criteria:

• Malignity or severe, competing medical or psychiatric disease

• Esophagitis (proven by endoscopy)

• Prior complication to peptic ulcer disease

• Alarm symptoms

• Pregnancy or lactation

• Allergy towards esomeprazole

• Planned hospitalisation during study period