Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas
Status:
Recruiting
Trial end date:
2040-10-01
Target enrollment:
Participant gender:
Summary
The prognosis for patients with localized pancreatic adenocarcinoma who are not surgical
candidates is poor. Patients characterized as having "borderline resectable" disease treated
with preoperative chemo-radiotherapy fair somewhat better - although many of these patients
are not converted to resectability. It may be argued that intensification of local and
regional therapy might 1.) Increase the share of patients able to undergo curative surgery
and 2.) Improve the local disease control interval and extend survival for patients who
remain unresectable. Therefore, the purpose of this research study is to determine if an
increase in the number of surgical resection pancreatic adenocarcinoma is higher than
historical data by using a combined treatment of proton radiation with capecitabine (oral
chemotherapy).